Obsessive-Compulsive Disorder (OCD)

Effectiveness and Neuropsychological Predictors of Guided Self-Help for OCD

Over the course of 17 weeks, participants in this study will use an internet program designed for treating OCD. They will meet with a therapist 9 times during the treatment. All participants will receive the treatment.

Hartford Hospital’s Institute of Living, Yale University School of Medicine
Principal Investigator: 
Gretchen Diefenbach, PhD
Eligibility Criteria: 

Individuals with the following may be considered for the study:

  • Principal or Co-Principal diagnosis of OCD
  • Age 18 – 69 inclusive
  • Y-BOCS score at least 16
  • CGI score at least 4 “moderately ill”
  • Able to be seen as outpatient
  • If on medications, stable type and dose for at least 4 weeks
Exclusion Criteria: 

Individuals with the following will not be considered for the study:

  • Active manic episode, active psychosis, pervasive developmental disorder, mental retardation
  • Concurrent OCD psychotherapy
  • Current threat of harm to self or others
  • Previous adequate trial of therapist-administered or self-administered ERP for OCD
Laura Bragdon, 860-545-7386, lbragdon@harthosp.org
Hartford, CT
Study End Date: 
Mon, 2014-09-01

BT Steps: A Study of Web-Based Treatment for Obsessive Compulsive Disorder

Do you have obsessive-compulsive disorder or think you might? Have you had trouble finding treatment for your OCD? Do you use the Internet? If you answered “yes” to these questions, you might be eligible to participate in a research study conducted by Dr. Kenneth Kobak of the Center for Psychological Consultation.

Center for Psychological Training, Research and Consultation
Principal Investigator: 
Kenneth Kobak, PhD
Eligibility Criteria: 

To participate in this study, you must be at least 18 years old, have OCD, and use or be willing to use the Internet. You will not be required to travel to participate in this study, as the BT Steps program is web-based and all coaching will take place via telephone.  Participants will be compensated up to $250 for their participation.

Revere Greist, (608) 556-0766, rgreist@centerforpsychconsulting.com
Study End Date: 
Mon, 2012-12-31

Recovery International

New Hampshire
Manchester, NH

If You Are Struggling With:

* Stress and Tension
* Anxiety
* Panic
* Depression
* Fatigue
* Insomnia
* Worry
* Fears
* Anger
* Obsessions
* Compulsions
* Feeling Helpless or Hopeless
* Other Emotional Problems

Recovery International can help you to help yourself!

Helping Children and Teens With Anxiety Disorders and Depression

Understanding New Research and Treatment

When anxiety takes over, it interferes with your child’s ability to cope with fear, worry, and depression — and treatment is necessary.

Early intervention is critical. Waiting for your child to mature or grow out of these behaviors may not be the right approach. In some cases children may develop chronic anxiety and depression, which is often associated with substance abuse and other high-risk behaviors.

Treating Children With Trichotillomania, Tics, and Tourette Syndrome

Martin Franklin, PhD

Associate Professor of clinical psychology in psychiatry
University of Pennsylvania School of Medicine

Director, Child & Adolescent OCD, Tics, Trichotillomania and Anxiety Group at the University of Pennsylvania School of Medicine (COTTAGE)

Dr. Franklin discusses treatment for children with trichotillomania, Tourette Syndrome, and other body-focused repetitive disorders and their relationship to anxiety disorders.


Seattle OCD Support & Recovery Group

Seattle, Washington

OCD Seattle

Seattle, WA

Potential Adjunctive Treatment for OCD Patients who do not Adequately Respond to Treatment with a Serotonin Reuptake Inhibitor

Need more help for your OCD? Many people with OCD experience only a partial response to currently available medications.

Emory University and multiple sites across the U.S. are seeking volunteers to participate in a clinical trial evaluating the effectiveness of low-dose ondansetron augmentation for the treatment of OCD in patients who have not adequately responded to their current SRI therapy after at least 12 weeks of stable treatment.

Emory University
Principal Investigator: 
Barbara Rothbaum, PhD
Eligibility Criteria: 

Participants must have a DSM-IV-TR diagnosis of OCD as their primary disorder who have been on a stable treatment regimen of clomipramine, fluvoxamine, fluoxetine, paroxetine, or sertraline for at least 6 weeks may be eligible for this study. Six additional weeks of stable SRI treatment, without adequate clinical response, will be required prior to randomization, after which the participant will receive SRI plus study drug, for a total of 12 more weeks.

Exclusion Criteria: 

Exclusion critera include, but are not restricted to the following:

  • Failure to respond to more than 2 SRI treatments prior to current SRI
  • Hoarding as primary OCD symptom
  • Current or past medical history of schizophrenia or other psychotic disorders, schizotypal personality disorder, bipolar disorder, Tourette syndrome, autism or autistic spectrum disorders, eating disorders, PTSD
  • Requiring active behavioral therapy
  • History of drug addiction or drug, alcohol, or other substance abuse within the past 12 months
  • Currently taking, or having taken within the previous 8 weeks, any of the following: other SRIs, antipsychotic drugs, lithium, benzodiazepines or other anxiolytics, carbamazepine, oxcarbazepine, phenytoin, or other anti-depressants (including St. John's Wort)
  • Likely to use triptans at any time during the study
  • Belived to have suicidal or homocidal risk


Mark Burton, 404-727-3662, msburto@emory.edu

Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder (OCD)

This study is investigating what, if any, changes in brain chemistry take place in adults with OCD as a result of cognitive behavioral therapy (CBT). We will measure amounts and distribution of glutamate in the brain using MRSI (Magnetic Resonance Spectroscopic Imaging) scans before and after 4 weeks of CBT.

The study offers:

UCLA Semel Institute
Principal Investigator: 
Jamie Feusner, MD; Joseph O'Neill, PhD
Eligibility Criteria: 
  • Have no history of bipolar disorder, a psychotic disorder, or substance dependence
  • Are in good physical health
  • Have not already had more than 30 hrs of CBT for OCD
  • Are right-handed
  • Between the ages of 18 and 65
  • Either not taking psychiatric medications or on a stable dose of a serotonin reuptake inhibitor (only) for at least 12 weeks
Courtney Sheen, 310-206-0468, csheen@mednet.ucla.edu
Los Angeles

Contact ADAA

8701 Georgia Ave. #412
Silver Spring, MD 20910


Contact ADAA

Request Publications