At the Intersection: Mood or Anxiety Disorders and Substance Use Disorder
Supported by Janssen
Friday, April 7
2:30 – 6:00 pm
The Scientific Research Symposium (SRS) will bring together experts in the field to highlight links between mood or anxiety disorders and substance use from genetics, psychological, epidemiological, and treatment perspectives. The goal is to provide a comprehensive overview of the state of knowledge and discuss insights from the experts toward the development of new ways of identifying, individuals at risk, determining what treatments might be effective, and develop tools to quantify the prognosis of patients with mood, anxiety and comorbid substance use disorder.
Substance use is highly comorbid with mood1and anxiety2 disorders. Substance use emerges during early teens and twenties (see figure 1), but there are also indications that illicit drug use is on the rise among the elderly (see figure 2). Several neurobiological theories have been proposed for the increased incidents during adolescents, which involve the imbalance between increased reward-related processing and inadequate cognitive control3, which emphasis positive reinforcement processes4. On the other hand, there is also evidence that substance use and maintenance emerges because the individual aims to relieve aversive and painful conditions, which has been termed antireward processing5.
Martin P. Paulus, MD — Chair
Laureate Institute for Brain Research
Genome-Wide Association Study of Post-Cannabis Dependence Anxiety
Joel Gelernter, MD
Yale University School of Medicine
Self-Medication of Mood and Anxiety Symptoms with Alcohol and Drugs: Findings from Large Scale Epidemiologic Surveys
Jitender Sareen, MD
Drinking to Cope: Psychological Mechanisms of Substance Use
Sherry Stewart, PhD
Smoking and Trauma
Mark Powers, PhD
1. Cranford, J.A., Nolen-Hoeksema, S. & Zucker, R.A. Alcohol involvement as a function of co-occurring alcohol use disorders and major depressive episode: evidence from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend 117, 145-51 (2011).