Novel medication strategies targeting brain mechanisms in pediatric ocd

Eligibility Criteria

• 8 - 20 years

• Genders: both

• Key inclusion criteria: Primary diagnosis of OCD and currently on a stable and adequate dose of an SRI


Your child may be eligible to participate in this study if he/she is diagnosed with Obsessive-Compulsive Disorder.

Exclusion Criteria

• Lifetime diagnosis of: psychotic disorder, bipolar disorder, eating disorder, pervasive developmental disorder, mental retardation, or substance/alcohol dependence

• Current diagnosis of major depressive disorder, attention-deficit hyperactivity disorder (ADHD), Tourette’s/Tic Disorder, or substance/alcohol abuse

• Diagnosis of pediatric autoimmune neuropsychiatric disorders associated with streptococcus (PANDAS)

• Active Suicidal Ideation

• Hoarding as the primary OCD symptom

• Pregnant, nursing, or planning to become pregnant

New York

This study aims to determine whether adding a medication called minocycline to

antidepressant treatment can help reduce symptoms of OCD. This study also aims to

learn more about the brains of children and adolescents with OCD.


Your child must be taking a stable dose of a serotonin reuptake inhibitor (SRI) in order to

participate in this study. During the 12 week study period, your child will continue to

Mind Over Moods — Treating Coexisting Depression and Anxiety

Dennis Greenberger, PhD
Founder and Director
Anxiety & Depression Center
Newport Beach, California

Assistant Clinical Professor
Department of Psychiatry
University of California, Irvine, College of Medicine

Dr. Greenberger describes the differences and similarities between symptoms of anxiety and depression, how the disorders are treated, and what patients can expect in treatment.