News and Research

Reducing Relapse With Longer Therapy

Patients with GAD treated with venlafaxine hydrochloride extended release for 12 months have substantially lower relapse rates when they stop the medication than patients who stop the medication after 6 months. (Archives of General Psychiatry, 2010;67(12):1274-1281) Read more.

Heart Patients With GAD May Have Worse Outcomes

Researchers have identified a strong association between generalized anxiety disorder and cardiovascular events, including myocardial infarction, stroke, heart failure, or even death. (Archives of General Psychiatry, 2010; 67(7):750-758) Read more.   

Massage Effective Therapy for GAD

In a trial comparing the effects of massage on people with GAD, participants reported their anxiety reduced by 40 percent at the end of 12 weeks and by 50 percent three months later. Although effective, massage has not been proven to be clinically or statistically superior to either thermotherapy or relaxing room treatment. (Depression and Anxiety, published online February 23, 2010)

People With GAD Less Able to Regulate Emotions

According to a new study, people with generalized anxiety disorder (GAD) have abnormalities in the way their brain unconsciously controls emotions. The study’s authors suggest the findings could change our understanding of how emotions are regulated and open the way for new treatments. (American Journal of Psychiatry, published online February 1, 2010)

Perceived Control Over Anxiety-Related Events and Generalized Anxiety Disorder

Self-perceived control over anxiety-related events among adolescents related negatively to worry and to symptoms and diagnoses of GAD, according to the findings of a new study. (Journal of Abnormal Child Psychology, Feb. 2010; 38(2): 237-247)

Stress-Related Disorders Affect Memory

Using functional MRI (fMRI) in a study at University of Udine in Italy, researchers suggest that the area of the brain controlling the processing of memories is dysfunctional in patients who have stress-related disorders, including generalized anxiety disorder and panic disorder.
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CBT Provides Relief for Older Adults With GAD

Cognitive-behavioral therapy (CBT) in a primary care setting was found to relieve generalized anxiety disorder (GAD) in older patients, according to the findings of a study conducted at Baylor College of Medicine. In the older-adult population, GAD affects up to 7.3 percent and 11.2 percent in primary care. Late-life anxiety is usually treated with medication, which may be associated with falls, memory problems, and other issues.
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Quetiapine XR Shows Efficacy and Safety in Older Patients With Generalized Anxiety

New data show that quetiapine XR monotherapy effectively treats symptoms of anxiety in older patients with generalized anxiety disorder (GAD), and the benefit is seen as early as the first week of treatment, report investigators in a multicentre study.
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