More than one in 10 Americans take antidepressants, the number one type of medication used by people ages 18 to 44. Yet contradictory research and opposing perspectives from experts beg these questions: How do antidepressants work? How are drug trials conducted? And how can clinicians and doctors learn more about depression itself?

In this video, Jerrold F. Rosenbaum, MD, Massachusetts General Hospital chief of psychiatry, discusses the ups and downs of antidepressants.

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