Children

Treating Children With PTSD

Judith Cohen, MD

Medical Director, Center for Traumatic Stress in Children & Adolescents
Allegheny General Hospital
Pittsburgh, Pennsylvania

Professor of Psychiatry
Drexel University College of Medicine

Dr. Cohen discusses how children experience PTSD and effective treatments.

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New Personal Story of Overcoming OCD

7/15/2011

OCD burdened a bright young woman for more than 10 years. Read all about her recovery and her advice to others who are suffering in Working Toward Compassion and Moderation.

“I advise anyone dealing with OCD to find a competent therapist who specializes in this illness.”

The Throes of Severe OCD: a Mother’s Perspective

My son Dan was in college, and by the time I arrived at his dorm, he had not eaten in more than a week. He was spending hours at a time sitting in one particular chair, hunched over with his head in his hands, doing absolutely nothing. He could not enter most of the buildings on campus and could only do minimal amounts of work at specific times. To top it all off, he was self-injuring. My son was in the throes of severe OCD.

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Anxiety Disorders (Pediatric) Research Study

This study uses functional magnetic resonance imaging (fMRI) to learn how the brain functions in adolescents receiving fluoxetine (Prozac) or cognitive behavioral therapy (CBT) for anxiety or depression in children/adolescents. All participants will receive interviews to assess how they are doing in general, including his or her general mood, degree of nervousness and behavior. Each participant and one of his or her parents will be interviewed separately and together.

Organization: 
NIMH
Principal Investigator: 
Daniel S. Pine, MD; 301-594-9960, Daniel.Pine@nih.hhs.gov
Eligibility Criteria: 

JUVENILE SUBJECTS

Age: 8 to 17

Consent: Can give consent/assent. (Parents will provide consent; minors will provide assent.)

IQ: All subjects will have IQ greater than 70 (Assessment relies on WASI)

SUBJECTS WITH AN ANXIETY DISORDER

Diagnosis: Current Diagnosis of Social Phobia, Separation Anxiety, or Generalized Anxiety Disorder (Based on K-SADS)

Symptom Severity: Score greater than 9 on PARS (This score was used to enroll subjects in previous trial demonstrating efficacy of an SSRI in pediatric anxiety.)

Clinical Impairment: CGAS less than 60

SUBJECTS WITH A MOOD DISORDER

Diagnosis: Current Diagnosis of Major Depression (Based on K-SADS (juveniles) or SCID (adults))

Clinical Impairment: CGAS less than 60 (juveniles) GAS less than 70 (adults)

Symptom Severity: CDRS Score greater than 39 (juveniles) (This score was used to enroll subjects in previous trials demonstrating efficacy of an SSRI in pediatric depression.)

ADULT SUBJECTS

Age: 20-40

Consent: Can give consent/assent.

IQ: All subjects will have IQ greater than 70. Assessment relies on WASI.

Exclusion Criteria: 

ALL SUBJECTS:

Any serious medical condition or condition that interferes with fMRI scanning, and for patients electing medication, any condition that increases risk of SSRI treatment. All patients will have complete physical examination. Healthy volunteer participants will be medication-free and have no current serious medical conditions, based on a review of their medical history.

Pregnancy

Current use of any psychoactive substance; current suicidal ideation; current diagnosis of attention deficit hyperactivity disorder (ADHD) of sufficient severity to require pharmacotherapy. These factors could complicate treatment with an SSRI. No subject on medication will be accepted into the trial. Subjects will not be taken off of medications to enter the trial.

Current diagnoses: Tourette's, OCD, posttraumatic distress disorder, conduct disorder. These factors may be effected by SSRI treatment, influencing ability to detect effects on anxiety/depression

Past or current history of mania, psychosis, or pervasive developmental disorder. These factors may be effected by SSRI treatment, influencing ability to detect effects on anxiety/depression

Recent use of an SSRI: All subjects must have been free of any SSRI use for at least one month (fluoxetine six months) and must not have been treated with an SSRI for their current depressive episode. This is designed to exclude subjects who have failed a trial of an SSRI for their current episode of major depression.

HEALTHY ADULT SUBJECTS

Any current psychiatric diagnosis. Assessment relies on SCID.

SUBJECTS WITH AN ANXIETY DISORDER

Current Major Depressive Disorder

Contact: 
Allison M. Detloff, 301-451-6817, detloffa@mail.nih.gov
Location: 
Bethesda
State: 
Maryland
Study End Date: 
Tue, 2013-12-31

The Art of Persuasion: Changing the Mind on OCD

Reid Wilson, PhD

Director, Anxiety Disorders Treatment Center
Chapel Hill, North Carolina

Associate Clinical Professor of Psychiatry
University of North Carolina School of Medicine

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The Diane Rehm Show on Anxiety Disorders

The Diane Rehm Show, produced by WAMU in Washington, DC, for NPR, featured a program on anxiety disorders on November 18, 2010.

Listen to the show.

Read a transcript.

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Managing Holiday Anxiety and Depression

Out and About, or Stressed Out?


The hoHoliday dinnerlidays are an exciting time of good cheer, warm family traditions, and spending time with friends. Or, are they?

For many people, the idea of entering a crowded room and chatting up coworkers or strangers at a party, exchanging gifts with friends, traveling from home, or attending large family gatherings can produce intense anxiety, depression, or both.

Eating Disorders and Anxiety

Cynthia M. Bulik, PhD, FAED
William and Jeanne Jordan Distinguished Professor of Eating Disorders
Department of Psychiatry
University of North Carolina at Chapel Hill School of Medicine
Professor of Nutrition in the Gillings School of Global Public Health
Director of the UNC Eating Disorders Program

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News and Research

Cognitive-Behavior Therapy in Occupational Therapy

There has been an increasing trend in pediatric clients with mood disorders entering occupational therapy over the last few years. One practitioner discusses using cognitive-behavioral therapy (CBT), among other strategies, for pediatric clients. (Advance, 28(15):17)  Read more.

 

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