This study aims to determine whether adding a medication called minocycline to
antidepressant treatment can help reduce symptoms of OCD. This study also aims to
learn more about the brains of children and adolescents with OCD.
Your child must be taking a stable dose of a serotonin reuptake inhibitor (SRI) in order to
participate in this study. During the 12 week study period, your child will continue to
• 8 - 20 years
• Genders: both
• Key inclusion criteria: Primary diagnosis of OCD and currently on a stable and adequate dose of an SRI
Your child may be eligible to participate in this study if he/she is diagnosed with Obsessive-Compulsive Disorder.
• Lifetime diagnosis of: psychotic disorder, bipolar disorder, eating disorder, pervasive developmental disorder, mental retardation, or substance/alcohol dependence
• Current diagnosis of major depressive disorder, attention-deficit hyperactivity disorder (ADHD), Tourette’s/Tic Disorder, or substance/alcohol abuse
• Diagnosis of pediatric autoimmune neuropsychiatric disorders associated with streptococcus (PANDAS)
• Active Suicidal Ideation
• Hoarding as the primary OCD symptom
• Pregnant, nursing, or planning to become pregnant
ADAA helps people find appropriate treatment for anxiety disorders, depression, and related illnesses. And we support the psychologists, psychiatrists, social workers, and other professionals who help their patients. Read two stories of life-changing treatment that led to remarkable recoveries. With your help, we can continue to help all those in need of treatment.
Listen to Dr. Dennis Greenberger describe the differences and similarities between symptoms of anxiety and depression, how the disorders are treated, and what patients can expect in treatment.
Dennis Greenberger, PhD
Founder and Director
Anxiety & Depression Center
Newport Beach, California
Assistant Clinical Professor
Department of Psychiatry
University of California, Irvine, College of Medicine
Dr. Greenberger describes the differences and similarities between symptoms of anxiety and depression, how the disorders are treated, and what patients can expect in treatment.
Katharina Manassis, MD
Dr. Manassis addresses why children sometimes refuse to go to school, when school refusal become a serious problem, and helpful therapies.
What's complicated about grief? Listen here, and find out how it differs from bereavement and how it's treated.
Posttraumatic stress disorder, or PTSD, is diagnosed after a person experiences symptoms for at least one month following a traumatic event. The disorder is characterized by three main types of symptoms:
Find out what the experts know about treating trichotillomania (hairpulling)...and you don't. Clinicians: Learn about the roadblocks to treating PTSD and comorbid illnesses.
Nancy Keuthen, PhD
Co-Director, Trichotillomania Clinic and Research Unit
Chief Psychologist, Obsessive-Compulsive Disorder Clinic
Massachusetts General Hospital
Associate Professor of Psychology
Harvard Medical School