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Need more help for your OCD? Many people with OCD experience only a partial response to currently available medications.
Montefiore Medical Center and multiple sites across the U.S. are seeking volunteers to participate in a clinical trial evaluating the effectiveness of low-dose ondansetron augmentation for the treatment of
Participants must have a DSM-IV-TR diagnosis of OCD as their primary disorder who have been on a stable treatment regimen of clomipramine, fluvoxamine, fluoxetine, paroxetine or sertraline for at least 6 weeks may be eligible for this study. Six additional weeks of stable SRI treatment, without adequate clinical response, will be required prior to randomization, after which the participant will receive SRI plus study drug, for a total of 12 more weeks.
Exclusion criteria include, but are not restricted to the following:
• Failure to respond to more than 2 SRI treatments prior to current SRI
• Hoarding as primary OCD symptom
• Current or past medical history of schizophrenia or other psychotic disorders, schizotypal personality disorder, bipolar disorder, Tourette syndrome, autism or autistic spectrum disorders, eating disorders, PTSD
• Requiring active behavioral therapy
• History of drug addiction or drug, alcohol or other substance abuse within the past 12 months
• Currently taking, or having taken within the previous 8 weeks, any of the following: other SRls, antipsychotic drugs, lithium, benzodiazepines or other anxiolytics, carbamazepine, oxcarbazepine, phenytoin, or other anti-depressants (including St. John's Wort)
• Likely to use triptans at any time during the study
• Believed to have suicidal or homicidal risk
People often jokingly point to odd habits or tidiness as signs of obsessive-compulsive disorder, or OCD. But the truth is OCD is a very real disorder that affects more than 2 million Americans, and there is a big difference between maintaining a morning routine or keeping a clean home and living with the disorder.
We at the Bio-Behavioral Institute in Great Neck, NY are investigating the role of certain emotions in individuals with body dysmorphic disorder (BDD), obsessive-compulsive disorder (OCD), or hoarding.
Individuals who have been diagnosed with one or more of the following:
OCD burdened a bright young woman for more than 10 years. Read all about her recovery and her advice to others who are suffering in Working Toward Compassion and Moderation.
Episodic OCD burdened me for over a decade, from my college years until 2006. Self-punishment made matters worse, as it does for everyone. I compulsively checked the coffee maker to see if it was off, and overchecked my written work. I feared I had inadvertently written embarrassing or unkind Freudian slips.
My son Dan was in college, and by the time I arrived at his dorm, he had not eaten in more than a week. He was spending hours at a time sitting in one particular chair, hunched over with his head in his hands, doing absolutely nothing. He could not enter most of the buildings on campus and could only do minimal amounts of work at specific times. To top it all off, he was self-injuring. My son was in the throes of severe OCD.
The anxiety and shame started when Diance was 25. She was sitting in a pew at her church, where she is active in the ministry. It seemed to come out of nowhere. She felt as if she were going to jump out of her skin.
Diance doesn’t know why she felt so anxious. But she knows what she saw when the feeling overwhelmed her: a nearby woman wearing a v-neck sweater.