This study aims to determine whether adding a medication called minocycline to
antidepressant treatment can help reduce symptoms of OCD. This study also aims to
learn more about the brains of children and adolescents with OCD.
Your child must be taking a stable dose of a serotonin reuptake inhibitor (SRI) in order to
participate in this study. During the 12 week study period, your child will continue to
take the SRI s/he is currently taking. Your child will also be given another medicine to
take which will be either minocycline or pill placebo (a pill with no medicine in it). There
is a two out of three chance that your child will receive minocycline instead of placebo.
You, your child, and the study doctor will not know whether your child is receiving
minocycline or placebo until after the study is over, but the information will be available
in case of a medical emergency.