Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder (OCD)

This study is investigating what, if any, changes in brain chemistry take place in adults with OCD as a result of cognitive behavioral therapy (CBT). We will measure amounts and distribution of glutamate in the brain using MRSI (Magnetic Resonance Spectroscopic Imaging) scans before and after 4 weeks of CBT.

The study offers:

Diagnostic evaluation
4 weeks of FREE intensive CBT (exposure and response prevention): 90 minutes/day, 5 days/week
MRI/MRSI brain scans
Neurocognitive testing

Organization:

UCLA Semel Institute

Principal Investigator:

Jamie Feusner, MD; Joseph O'Neill, PhD

Eligibility Criteria:

Have no history of bipolar disorder, a psychotic disorder, or substance dependence
Are in good physical health
Have not already had more than 30 hrs of CBT for OCD
Are right-handed
Between the ages of 18 and 65
Either not taking psychiatric medications or on a stable dose of a serotonin reuptake inhibitor (only) for at least 12 weeks

Contact:

Courtney Sheen, 310-206-0468, csheen@mednet.ucla.edu

Location:

Los Angeles

State:

California